In Danganronpa 2, the player controls the main protagonist and playable character Hajime Hinata. This 'Anniversary'-branded version would also be released on the Nintendo Switch as part of Danganronpa Decadence and standalone in the Nintendo eShop in late 2021.

Like the previous game, an 'Anniversary Edition' for this title was launched for Android and iOS devices worldwide on August 20th, 2020 as part of the Danganronpa 10th Anniversary celebration. NIS America delisted their digital Vita version on Septemdue to this decision.

The PS4 version would be the last one from NIS America before Spike Chunsoft would take over English publishing of all Danganronpa games in the 2020s. A Steam version was released on April 18th, 2016 and a PlayStation 4 version of 1.2 Reload was released in March 2017 as well. NIS America localized and released this Vita version standalone in September 2014 in North America and Europe. Each game in this collection had improved graphics and additional content. It was re-released on October 10th, 2013 as part of Danganronpa 1.2 Reload, a compilation for the PlayStation Vita containing this game and Danganronpa: Trigger Happy Havoc. The game was first released in Japan on July 26th, 2012 for the PlayStation Portable. It is the second main title in the Danganronpa series and is a sequel to Danganronpa: Trigger Happy Havoc. Danganronpa 2: Goodbye Despair (in Japan: スーパーダンガンロンパ2 さよなら絶望学園 ) is a Japanese visual novel game developed by Spike Chunsoft.

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